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This form of preparation has many advantages, such as convenient administration, high patient compliance, and the ability to avoid first pass effects in the liver
Start low, even coming from a high dose Most switch protocols start tirzepatide at 2.55 mg/week regardless of the semaglutide dose someone was previously on, then re-titrate from there to limit GI side effects
The exact number can vary depending on the study, but it is generally less than 10% of users
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