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It also supports healthy inflammatory balance through multiple pathways. 25 Vitamin C supports histamine degradation and may support a healthy response to oxidative stress from the inflammatory response. 26 Bromelain (from pineapple) is a protein-digesting enzyme that enhances quercetin absorption and has its own properties that support a healthy inflammatory response. 27 Quercetin isn't well absorbed on its own, so the bromelain is particularly important

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Taylor and Francis+NEJM , doi:10.1080/096374080410001666504

The experiment investigated the potential cytotoxicity of these factors using in vitro keratinocyte and fibroblast cell assays