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According to the post-hoc analysis of SURPASS-3 (NCT03882970), 52 weeks of tirzepatide treatment resulted in a 4.4% reduction in MFI in individuals with T2DM [85]

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Because its a stimulant, the phentermine label warns about increases in blood pressure, insomnia if taken late in the day, and its contraindicated in people with a history of cardiovascular disease, uncontrolled hypertension, hyperthyroidism, glaucoma, agitated states, or a history of drug abuse

10.1093/femsyr/fow054 FEMS Yeast Res