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GLP-1RAs also exert anti-arrhythmic effects via reducing calcium leak from the sarcoplasmic reticulum in ventricular arrhythmia, which has the potential to decrease phosphorylation of the type 2 ryanodine receptor (RyR2) and alleviate the activity of CaMK-II [77]
Avoid bupropion in patients with eating or seizure disorders, avoid naltrexone in opioid users and patients with liver dysfunction, and use caution when prescribing topiramate to pregnant women or women on birth control pills
Archived from the original on 7 February 2019
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