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Conclusion Health insurers are likely to be or have already been exposed to the rise of GLP-1s, and the exposure is expected to expand with approvals for new indications in the pipeline, as well as a projected increase in take-up rates

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The management of type 2 diabetes necessitates in-person monitoring, regular lab tests, and physical exams which cannot be effectively conducted through telehealth platforms

The recognition that native GLP-1 is quickly degraded by the protease dipeptidyl peptidase IV (DPP-4) led to the development of GLP-1 agonists that are resistant to this enzyme [37]