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When the levels of these free radicals become too high in the brain, the body no longer has enough antioxidants to remove them all
Studies in animal models show consistent effects on gut wall integrity, including reduction of intestinal permeability markers associated with leaky gut
The tendency for some individuals to have received DPP-4is before switching to GLP-1 RAs may account for the longer diabetes duration and the slightly higher prevalence of diabetic complications and hypertension in the GLP-1 RA group
This is where most damage occurs
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