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GIP receptor activation in adipose tissue influences lipid storage and mobilization, and in the brain, it contributes to appetite regulation through mechanisms that complement GLP-1 signaling

Semaglutide, a glucagon-like peptide receptor agonist (GLP- 1 RA), was shown in STEP 1 to produce mean weight reduction from baseline to week 68 of 14.9% for semaglutide versus 2.4% for placebo, by treatment-policy or treatment-regimen estimand which is reported throughout this manuscript, except where noted [1]

As far as the brand is concerned, it is not stated anywhere in the package if it is safe to use for lactating women

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