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[67] [68] Epidemiology [edit] PA is estimated to affect 0.1% of the general population and 1.9% of those over 60, accounting for 2050% of B 12 deficiency in adults
For individuals with conditions that affect B12 absorption, such as pernicious anemia or gastrointestinal disorders, monitoring helps to track the progression of the disease and the effectiveness of treatment
For higher concentrations, some protocols utilize a small percentage of DMSO or Ethanol before aqueous dilution
In a statement, the FDA commissioner, Martin Makary, said the drug would now be approved for patients with cerebral folate deficiency (CFD), a condition sometimes associated with autism spectrum disorders
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