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doi: 10.3389/fbioe.2023.1161472 Received 08 February 2023 Accepted 24 February 2023 Published 10 March 2023 Volume 11 - 2023 Edited by Wen Sun, Dalian University of Technology, China Reviewed by Xin Liu, The University of Chicago, United States Xiaobo Wang, Fourth Military Medical University, China Updates Copyright 2023 Liu, Hao, Liu and Hu
Evidence for differential catalytic activity of the encoded proteins
These experiments confirmed that cagrilintide is a potent dual agonist, activating both receptor types, which is crucial for its therapeutic effect on reducing food intake and body weight, as demonstrated in preclinical rat models
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