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Patients who inject 7 days a week thinking more is better typically blunt their own response by week 6

This can lead to cloudy vision, poor sight in dark conditions and at night, and even permanent vision loss

Metabolic Benefits: Research indicates that the GIP component may also contribute to other metabolic advantages, such as potentially reducing fat accumulation and improving overall metabolic efficiency

In a single piece, he concisely captures: the state of the field the most important clinical trials where the pipeline is headed These Clinical trials are raising the bar and expanding future treatment options: Retatrutide ~24% weight loss (triple agonist) MariTide 1216% weight loss (GLP-1 + GIP antagonist) CagriSema up to 20% weight loss + ~2% HbA1c drop Orforglipron oral GLP-1, HbA1c 1.5%, weight 7.6% IcoSema weekly semaglutide + once-weekly insulin Even more exciting