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Potential Adverse Effects The FDA flagged concerns about: Immunogenicity and antibody formation with repeated dosing Peptide-related impurities from compounding pharmacy manufacturing Unknown effects on cardiovascular, hepatic, and renal function with chronic use Theoretical acceleration of undetected tumor growth Current Research Gaps The literature reveals critical knowledge deficits preventing definitive cancer risk conclusions: Long-term human safety: No prospective study has followed BPC-157 users for months or years to document cancer incidence or tumor progression
Clinical Nutrition, 39(5), 1391-1400
Epitalon appears broadly safe for human use, but critical safety testing is lacking even with the peptides relatively long research timeline
Expert Opin Biol Ther
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