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It is truncated analogue of growth hormone releasing hormone (GHRH), which was developed in 1980s from original GRF 1-29, but with purposefully prolonged half-life to ensure better therapeutical use
Significant overproduction of POMC, ACTH, and MSH promotes the anorexigenic pathway, resulting in poor oral intake
The difference in concentration patterns (lower peaks, higher troughs) is modest enough that major safety divergence seems unlikely
Whilst both supplements have individual evidence for modest metabolic effects, their combined use specifically for weight loss remains under-researched
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