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Health insurers need to consider the potential impact of multiple aspects, including benefits and coverage and cost implications and controls

RNA-based silencing (RNAi/miRNA) RNA interference techniques use small RNA molecules (siRNA, miRNA) to silence the expression of pathogenic genes post-transcriptionally, such as genes involved in autoimmune antigen presentation or proinflammatory signaling

An intramuscular injection (IM injection) is a medical technique used to deliver medication directly into muscle tissue, where it can be absorbed quickly into the bloodstream

Human safety is not established because large human trials have not been completed