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Matching Peptide Characteristics to Application Needs Companies working on making the next wave of medicines to treat obesity may choose GLP-1 peptide Cagrilintide because it has a new way of working and could be used with other medicines, which could help them stand out in the crowded GLP-1 market

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This observation may explain why semaglutide and other GLP-1 RAs ranked among the lowest-impact DM2 DMTs in our model compared to drugs such as metformin, which engage a broader range of metabolic and neuroprotective pathways (e.g., AMPK, insulin, and adipocytokine signaling)