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In these studies, the primary endpoint was change from baseline in HbA1c after 26 weeks of treatment evaluated by the treatment policy estimand, and oral semaglutide 14 mg was associated with a superior reduction in HbA1c compared with empagliflozin 25 mg and sitagliptin 100 mg, and a non-inferior reduction in HbA1c compared with liraglutide 1.8 mg
[Abstract]2025 Jan;87(1):159-169
One of the functions GLP-1 serves is to stimulate natural insulin production, and to inhibit glucose production, which makes these drugs effective at lowering blood sugar in people with diabetes
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