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When vaccines were tested, rhesus macaques immunized with purified -propriolactone-inactivated SARS-CoV-2 in alum showed complete or partial protection against high-inoculum SARS-CoV-2 challenge, and histopathological analyses of lungs and other organs at 29 days showed no evidence of ADE of disease compared with control macaques 132

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Based on brief discussion of the variability in the applied techniques and a comprehensive analysis of the physiological variability in the literature, evidence-based recommendations will be formulated for future studies aiming to achieve a more standardized approach for RBF quantification

De meest gedocumenteerde onderzoeksgebieden zijn melanogenese en fotoprotectie, neuro-endocriene regulatie, metabolisme en neuro-immuunmodulatie