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The extract effectively suppressed IgG2a, IgE, eosinophilia, and mucus hypersecretion and significantly inhibited the increase in mRNA expression and Th2-type cytokines, including IL-5 and IL-4 in lung tissue and bronchoalveolar lavage fluid (BALF) in the asthmatic mouse model
By means of the enzyme lysine-specific demethylase (LSD-1), it ensures the demethylation of histones, whereby some genes are increasingly expressed
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