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Electronic databases including PubMed, Embase, and Web of Science were searched from inception until August 2025 using keywords such as GLP-1 receptor agonist, diabetic retinopathy, glaucoma, age-related macular degeneration, ocular disease, and neuroprotection. The search focused on identifying preclinical studies, large-scale retrospective cohort studies, and post-hoc analyses of major clinical trials that evaluated the utility and potential mechanisms of GLP-1RAs in ophthalmic diseases
Fat Loss and Water Weight In the early stages, some weight loss may be due to reduced water retention
Some people describe new confidence and openness to intimacy, while others notice lowered desire, possibly due to brain reward pathway changes (Wired, 2024)
Additionally, SELENOP expression was most robust in the choroid plexus and regions lining the brain ventricles (Sasuclark et al., 2019), which is in line with the previous studies (Rueli et al., 2015)
