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86 These interesting findings force us to reconsider the effect of the ethnic differences in IR, which is important to reduce the morbidity and mortality related to diabetes mellitus and metabolic syndrome
A large proportion of these studies reported on the impact of GLP-1RAs on dopaminergic neurotransmission responsible for reward processingwhich could contribute to their efficacy as anti-obesity medications by means of a reduction of food-related incentive 110
While the studies published to date have limitations, there are several ongoing investigations, including the pivotal FOCUS trial, conducted as a post-authorization safety commitment to the European Medicines Agency
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