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[18] Many molecular events discussed alongside AOD9604such as cyclic AMP accumulation, protein kinase A activation, hormone-sensitive lipase phosphorylation, perilipin remodeling, and mitochondrial fatty-acid oxidationbelong to established adipocyte biology

The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]

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