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The administration of Total Cistanche polysaccharides effectively mitigated the inflammatory response in the colon and ameliorated gut barrier disruption by modulating the dysbiosis of gut microbiota in rats subjected to chronic unpredictable stress, indicating that the antidepressant effect of Cistanche polysaccharides is also associated with their regulation on gut microbiota (Fan et al., 2021)

This current study by Ekarattanawong et al

Glutathione can be broken down in the bodys digestive system

This is why many people who struggle with blood sugar management also have low levels of this critical antioxidant