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The GSSG concentration was also significantly higher in alcoholics (8.2 0.3% of total) and nonalcoholics (8.5 0.8% of total) than in control subjects (4.4 0.2% of total), reflecting an abnormal balance between GSH and GSSG in these patients
Administration of cortex of Paeonia suffruticosa Andrews could prevent liver injury by decreasing ALT, protecting against hepatic glutathione depletion, attenuating cytochrome P450 2E1 activity, and preventing hepatic DNA damage in vivo
This combination is particularly effective in patients who have Hashimotos thyroiditis with otherwise normal thyroid levels or who are subclinically hypothyroid
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