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Patients with diabetes who are initiating GLP-1 RAsespecially those with elevated baseline hemoglobin A1c or anticipated rapid reductionmay benefit from being monitored more closely than suggested by the American Academy of Ophthalmology preferred practice pattern, which is based on the current level of retinopathy

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Human studies on the analgesic efficacy of liraglutide in KOA have yielded inconclusive results

[1] It may potentially interact with specific receptors in the pituitary and the hypothalamus, known as GHRH receptors