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The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
Reversing vitamin B12 deficiency is possible using this frequency
However, the study lacked a placebo control, and the increases were not dramatically better than those seen with regular (non-liposomal) glutathione at similar doses in the Richie et al
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