The short half-life (12 min in humans) results from dipeptidylpeptidase-IV (DPP-IV) proteolysis by which the N-terminal dipeptide is rapidly removed, inactivating GLP-1
Omatseye Jr., MD, aesthetic and regenerative medicine provider at Signature Rejuvenation MD in Florida, says your sex, body weight, and age wont change the timeline, but any medication or health condition (e.g., severe renal failure) that decreases Wegovys breakdown in the body will make it take longer
GLP-1 medications, or glucagon-like peptide-1 receptor agonists, treat type 2 diabetes and, in some cases, obesity
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