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Doses increase weekly during the first two months, then hold steady at a maintenance level

A weak intensity was considered positive when the stained cells accounted for more than 5% of the whole tumor section

Due to potential environmental sustainability concerns (collection of the hemolymph used in pharmaceutical testing may negatively affect horseshoe crab populations), a quantitative and more sensitive endotoxin assay was developed using a pyrogentesting cell model with knock-in of TLR4/CD14/MD2 at the safe harbor locus AAVS