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On April 30, 2026, the FDA proposed to formally and permanently exclude semaglutide, tirzepatide, and liraglutide from the 503B outsourcing facility bulk drug substances list
This reduces dysfunction of the nerves and slows down and/or prevents progression of nerve pathology often seen in peripheral neuropathy
Experimental studies have also pointed to a direct ICP-lowering effect of GLP-1RAs
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