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Furthermore, TMAO increased aortic plaque area and altered bile acid composition in male ApoE (-/-) mice, accelerating aortic lesions by modifying bile acid profiles, activating FXR and small heterodimer partner, and inhibiting bile acid synthesis (136)

A 140-pound woman who consumed just as many drinks in one hour has a BAC of 0.048

Functional Medicine 2.0 builds upon that foundation, using systems biology (how all body systems communicate), genetics (your inherited blueprint), and bioenergetics (how your cells make and manage energy) to build resilience