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In contrast, multiple rodent pulmonary hypertension models demonstrate that GLP-1 receptor agonists, including exendin-4 and liraglutide, reduce vascular remodelling, inflammation, and ventricular hypertrophy via endothelial nitric oxide signalling and suppression of endothelin-1 pathways [68,69,72,73]

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17 studies were initially identified, but 10 studies were excluded due to lacking or unusable data

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interquartile range, 6.1% to 6.6%) or highest decile (median = 10.5%

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