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This study was part of the ToPiND trial that explored the activities of PIO and TOFO in 40 patients with T2D and NAFLD [117]
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Which symptoms require immediate medical attention, and which can be managed at home
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Future prospective comparative studies and large-scale real-world registries with robust control of confounding factors are warranted to define optimal treatment strategies and long-term clinical outcomes
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However, the innovations of GLP-1s meant they could mimic the hormone GLP-1 and be resistant to the DPP4 enzyme, so they had a lasting impact on blood sugar levels and appetite
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