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Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis

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In 2003, a study of 495 cancer trials between 1997 and 2000 indicated that elderly participants comprised 32 percent of participants in Phase 2 or 3 clinical trials, compared with 61 percent of patients with incident cancers in the United States who are elderly (Lewis et al., 2003)

Aroda VR et al