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Adults with SPCD must still avoid prolonged fastingwhich generally means skipping meals during the day, fasting for religious reasons, or fasting prior to medical procedures/bloodworkand must take their prescribed L-carnitine consistently to avoid muscle breakdown ( rhabdomyolysis ) and other complications [10] [6]
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Native IGF-1 binds IGFBP-3, the dominant carrier protein in circulation, with a dissociation constant in the low nanomolar range (Kd approximately 0.1 to 1 nM in most published binding assays)
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