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The clinical research currently consists of the following: Small 1980s pilot trials No large modern RCTs Limited pharmacokinetic clarity No validated subcutaneous dosing protocol for improved sleep DSIP likely works for many individuals, but its critical to acknowledge the doses used by the biohacking community comes from extrapolation

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Subsequent work established the saturation dose of approximately 1 mcg/kg IV, producing peak GH levels of 15 to 50 mcg/L in healthy subjects

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Gonzalez-Cadavid, N

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Topical Application (Primary Route for Hair) Topical GHK-Cu delivers the peptide directly to the scalp, where it can interact with dermal papilla cells and the follicular stem cell niche without systemic dilution

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