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Drugs best known for treating diabetes and obesity may also dampen the powerful cravings that drive addiction
Obesity reduced the anti-cancer effects of the antidiabetic adiponectin receptor agonist AdipoRon in diet-induced obese mice with orthotopic pancreatic cancer through a mechanism involving IGF-1, IGF-1R, and ERK1/2 signaling (5), indicating the importance of weight loss in combating pancreatic cancer in obese patients
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