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Acquired megacolon is an extremely enlarged colon that can result from prolonged severe constipation and that may require surgical treatment

Subcutaneous injection site reactions: prevention and treatment. Practical Pain Management , 18(6), 5056.

In fact, to the best of our knowledge, there are no studies focused on PE or habitual physical activity level and vitiligo disease, although several studies with similar etiological factors have consistently identified significant associations between vitiligo (as well as its severity) with MetS (Sharma et al., 2017

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