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The CagriSema metabolic preservation mechanism, specifically the maintenance of mitochondrial function in skeletal muscle during weight loss, could theoretically slow the rate of weight regain by preventing some of the metabolic adaptation that makes regain almost inevitable
[12] Blundell J, et al
10.1001/jama.2021.4788 10 ChenH.WangS.SongM.YangD.LiH
Commonly affected areas include the shoulders, elbows, hips, knees, and heelsplaces where repetitive movement or pressure causes irritation
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