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On the other hand, mitochondria-derived ROS increased secretion of neuropeptide FMRP-like peptide (FLP-1) in AIY interneurons, which in turn induced a major antioxidant mechanism, Nrf2, to eliminate excess ROS and ameliorate oxidative stress (Jia and Sieburth 2021)
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Other patients reported self-limited rectal bleeding not requiring active management (19 patients, 51.4%) or did not report any rectal bleeding (9 patients, 24.3%)
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