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Currently, two viable therapeutic approaches seem to have been identified, namely TAAR1 agonism and agmatine administration
Tumour resection (of chemo-naive) samples were previously transcriptionally profiled, and data are available from the Gene Expression Omnibus (GEO) (GSE103479)
We found that tamoxifen at concentrations, which accumulate in tumors during therapy, increases oxidative stress in ER-positive and ER-negative breast cancer cells, resulting in cell death
It also boosts metabolic efficiency, enhances endurance, and supports muscle recovery, making it particularly beneficial for athletes
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