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1l) and correspondingly lower RER but similar energy expenditure and ambulatory activity (Extended Data Fig
This is why dosing typically occurs weekly rather than daily, a significant advantage for research protocols and compliance
Research into metabolic effects of GLP-1 receptor agonists shows these medications can influence energy expenditure and substrate metabolism
In the case of diabetes, metformin (a tablet that helps the body to better use the insulin it produces) still remains the treatment of choice
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