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For example, the expression of ALOX15 is mediated by spermidine/spermine N1-acetyltransferase 1, a tumor protein p53 (TP53) target gene, and is involved in TP53-mediated ferroptosis (Ou et al., 2016)

This direct delivery method provides significantly more powerful and immediate benefits than what can be achieved with oral supplements

Additionally, increasing the intake of foods rich in antioxidants (vitamin C, E, selenium) and phytoestrogens (soy isoflavones, flaxseed lignans) can assist in alleviating menopausal symptoms and oxidative stress damage