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Following weight loss, reductions in both FFM and REE typically occur, lowering total energy expenditure and predisposing individuals to weight regain
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These include: -Severe skin reactions like rashes, hives, redness -Thyroid dysfunction -Abdominal pain -Kidney dysfunction leading to renal failure -Liver dysfunction A Word of Caution
The liver clears it almost entirely through cytochrome P450 3A4 (CYP3A4), producing inactive pyridine metabolites that are excreted in urine [1]
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