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Continuous numeric outcomes were tested for logarithmic (log) normality

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Baseline estimated renal function was normal (eGFR 90 mL/min/1.73m 2 ) in 63.1%, mildly impaired (eGFR 60 to 90 mL/min/1.73m 2 ) in 34.3%, and moderately impaired (eGFR 30 to 60 mL/min/1.73m 2 ) in 2.5% of the patients

[4] [5] In the brain, GLP-1 receptor activation in appetite-regulating centers reduces hunger and increases satiety, leading to decreased caloric intake and weight loss