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In addition, we applied maximum likelihood estimation and the Robust Adjusted Profile Score (RAPS) method to account for potential measurement error and weak instrument bias

Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk

Each laboratory should still validate performance with its own instruments, plates, and detection chemistry