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Tirzepatide is a different molecule (a dual GIP/GLP-1 agonist) that produces greater average weight loss in head-to-head trials
This starting dose is not meant to produce significant weight loss on its own
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Simultaneously, semaglutide suppresses glucagon secretion from pancreatic alpha cells primarily during hyperglycemia, while generally preserving counterregulatory glucagon responses during hypoglycemia
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