Some rare sermorelin side effects can include ( 6 ): Allergic reactions, such as rash, itching, or in severe cases, difficulty breathing Sleep disturbances, including vivid dreams or insomnia Water retention, bloating, or swelling in the hands and feet Joint pain or stiffness, particularly in the knees or ankles Tingling or numbness in the extremities These effects can sometimes be related to how the body processes increased GH levels
For example, the senescence of cardiac endothelial cells may exacerbate myocardial ischemia and heart failure
It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity
The peptide is usually injected subcutaneously, with the injection site often in the lower abdomen near the stomach for quick entry into the bloodstream