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Tolerability is another important factor
Uncontrolled hyperthyroidism can affect heart rate and cardiovascular function, which should be stable before adding medications that affect metabolism and weight
[11] 9 kg/m in certain circumstances)
The SUSTAIN-6 trial showed a significant reduction in major adverse cardiovascular events (MACE), including non-fatal myocardial infarction and non-fatal stroke, specifically in patients with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors
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