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Long-Term Safety Considerations Because Retatrutide is still in Phase 3 clinical trials, there is limited information about its safety profile beyond one year of treatment
In particular, in the L-carnitine group, 14 out of 18 subjects (77.8%) had a significant reduction of Lp(a) vs only 7 out of 18 (38.9%) in the placebo group (chi 2 = 4.11, p = 0.0452)
Patients need to be screened for contraindications (pregnancy/breastfeeding, cancer, metabolic diseases, hormone imbalance and certain types of medications)
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