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10.3969/j.issn.1001-1528.2018.09.002 30 YangS.ZhangW.XuanL
Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model
Variants that reduce CYP activity can slow initial metabolism, but if phase II is also impaired, reactive metabolites can still accumulate and damage DNA, mitochondria, and tissues like the liver and kidneys
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