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Phosphodiesterases (PDEs) are significant regulators of the duration and magnitude of cAMP signaling
Baseline mean (SD) FibroScan VCTE was 13.3 (6.8), 13.6 (7.1), and 12.9 (5.6) kPa for the resmetirom 80mg, resmetirom 100mg, and placebo groups
More importantly, the weight loss achieved by month 15 was maintained through month 24 with continued treatment
That effect levels the playing field, said Saunders, making it easier to adopt healthy habits like eating less and moving more
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