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After 6 and 12 months, growth rates, IGF-I, and GH-binding protein (GH-BP) levels increased similarly in all groups, indicating that GH timing does not affect treatment efficacy ( Exploring whether metabolic effect of growth hormone is equally beneficial with morning versus evening growth hormone (GH) injections in GH-deficient patients is crucial for tailoring optimal treatment plans for metabolic stability and overall health

PMID: 57 TavaresWDruckerDJBrubakerPL

GH secretagogue peptides work through the somatotropic axis, stimulating the pituitary to release your own growth hormone in a physiological pattern